Observational Study
researchers track health outcomes over time in groups of participants to look for patterns that help us better understand a disease.
Genetic Study for Kidney Patients
Genetic Research into FSGS, Nephrotic Syndrome, Unexplained Proteinuria, and Unexplained Kidney Failure
The Laboratory of Inherited Kidney Disease at Beth Israel Deaconess Medical Center and Harvard Medical School in Boston, Massachusetts, directed by Dr. Martin Pollak, seeks to identify genes that underlie the development of FSGS and similar diseases.
Trial Physician / Study Coordinator
Andrea Knobb at The Pollak Lab
Email Phone 617-667-0467Site Name
The Pollak Laboratory of Inherited Kidney Disease
Research North 304, 99 Brookline Avenue, Boston, MA 02215
Observational Study
researchers track health outcomes over time in groups of participants to look for patterns that help us better understand a disease.
Genetic Study for Kidney Patients
Genetic Research into FSGS, Nephrotic Syndrome, Unexplained Proteinuria, and Unexplained Kidney Failure
The Laboratory of Inherited Kidney Disease at Beth Israel Deaconess Medical Center and Harvard Medical School in Boston, Massachusetts, directed by Dr. Martin Pollak, seeks to identify genes that underlie the development of FSGS and similar diseases.
Eligibility Criteria
Patient Population
Primary focal segmental glomerulosclerosis (FSGS), nephrotic syndrome, unexplained proteinuria, and/or unexplained kidney failure
Age
0 — 26+
History of transplant allowed?
Yes, No
History of dialysis allowed?
Yes, No
eGFR
15 — > 60
UPCR
1.0 or Less — 3.0 or Above
Permitted medication history
Ace Inhibitors/ARB, Prednisone (Steroids), Abatacept, Acthar, Cellcept (AKA Mycophenolate), Cytoxan (Cyclophosphamide), Prograf (AKA Tacrolimus), Rituximab (AKA Rituxan), Other, None
Patient should be
Treatment Resistant, Steroid Dependent, Neither of These
About the Drug
What is involved for the patient
Patients will share a saliva sample with the lab. The kit will be mailed to the patient, and the patient will then mail their sample back to the lab.
Sponsor
The Pollak Laboratory of Inherited Kidney Disease
About the Trial
Study Goal
The Genetic Research Study hopes that by identifying genetic causes of kidney disease, better treatments can eventually be made for patients living with these conditions.
About the drug or intervention
Learn more at https://sites.google.com/site/pollakfsgs/home