Nephrotic Syndrome can be “primary” or “secondary” in nature.
Diseases that affect only the kidneys are called primary causes of Nephrotic Syndrome. Doctors often call these diseases “idiopathic,” which means that they arise from an unknown cause. Some of these diseases include:
- Minimal Change Disease (MCD) – most common in children
- Focal Segmental Glomerulosclerosis (FSGS)
- Membranous Nephropathy (MN) – most common in adults
- IgA Nephropathy (IgAN)
Secondary Nephrotic Syndrome is caused by an underlying, systemic condition like diabetes, lupus, HIV, and others.