Observational Study
researchers track health outcomes over time in groups of participants to look for patterns that help us better understand a disease.
The TANGO Study
The TANGO Study for Post-Transplant Glomerular Diseases
The TANGO study aims to create a large international network of centers to study glomerular disease (GN) recurrence after renal transplantation.
Trial Physician / Study Coordinator
Maria José Pérez-Sáez
Email Phone 617-726-6506Site Name
Hospital del Mar
Passeig Marítim de la Barceloneta, 25, 29, 08003 Barcelona, Spain
Observational Study
researchers track health outcomes over time in groups of participants to look for patterns that help us better understand a disease.
The TANGO Study
The TANGO Study for Post-Transplant Glomerular Diseases
The TANGO study aims to create a large international network of centers to study glomerular disease (GN) recurrence after renal transplantation.
Eligibility Criteria
Patient Population
The TANGO study will enroll adult (≥18 years) patients with a biopsy-proven primary Glomerular Disease (IgA nephropathy, Membranous glomerulonephritis, Focal and segmental glomerulosclerosis, Atypical hemolytic uremic syndrome, Membranoproliferative glomerulonephritis old classification type I-III, Complement- or IgG-positive membranoproliferative, glomerulonephritis, Dense-deposit disease, C3 glomerulonephritis) as the designated cause of their end-stage kidney disease who underwent a kidney transplant starting in January 2005 or later.
Age
18 — 26+
History of transplant allowed?
Yes
History of dialysis allowed?
Yes, No
eGFR
15 — > 60
UPCR
1.0 or Less — 3.0 or Above
Permitted medication history
Ace Inhibitors/ARB, Prednisone (Steroids), Abatacept, Acthar, Cellcept (AKA Mycophenolate), Cytoxan (Cyclophosphamide), Prograf (AKA Tacrolimus), Rituximab (AKA Rituxan), Other, None
Patient should be
Treatment Resistant, Steroid Dependent, Neither of These
About the Drug
What is involved for the patient
Your clinical information and samples (blood and urine) will be analyzed anonymously. This will help better understand individual diseases and potentially identify new potential treatments. You may choose to be contacted in the future as discoveries are made and potential novel treatments become available for your condition.
About the Trial
Study Goal
The purpose of the TANGO study is to create a large international network of centers to study kidney disease that recur after renal transplantation. Since many of these kidney diseases that recur are rare, it is crucial that we involve many centers around the world to collect individualized information that will help to understand the disease and identify new treatments.
About the drug or intervention
Learn more at http://tangoxstudy.com