Do you have a rare kidney disease like FSGS, IgA Nephropathy, or other Nephrotic Syndrome condition? You’ve come to the right place.
Access breakthrough clinical trials, expert care, and one-on-one patient support here.
Currently Enrolling
El Paso, TX
The AURONA Trial

Dose-Exploration Evaluating the Efficacy and Safety of Voclosporin in Subjects With Focal Segmental Glomerulosclerosis (AURONA)

Brief Description

This study will evaluate the safety and efficacy, measured by reaching complete or partial remission, of voclosporin for FSGS patients.

Trial for people with

Primary focal segmental glomerulosclerosis (FSGS)

Study Goal

The aim of this trial is to assess the efficacy of voclosporin (VCS) in achieving complete or partial remission of proteinuria after 24 weeks of therapy in patients with focal segmental glomerulosclerosis (FSGS). Also, the team will assess the safety and tolerability of VCS over 24 weeks.

What is involved for the Patient?

Patients will receive the study drug (softgel capsules) for 24 weeks.

About the drug or intervention

Voclosporin is an immunosuppressant drug.

  • Study CoordinatorKrista Piper
  • Study Coordinator
  • Study Coordinator Phone441 753 852132 ; 1-778-788-5577
  • Site NameFSGS Investigative Center
  • SponsorAurinia Pharmaceuticals Inc.
  • Study DrugVoclosporin
  • Estimated enrollment25
  • Estimated end dateMarch, 2020
If there is not a site for a clinical trial nearby, you can ask the study team about the possibility of travel reimbursements (i.e., paying you back for your travel costs). Alternatively, you can ask about the possibility of participating from home.
Frequently Asked Questions

Nephrotic Syndrome is not a disease itself, but rather a group of signs and symptoms that result from damage in the part of the kidney that filters blood (glomeruli).

Common symptoms include:

  • Foamy urine (called proteinuria) caused by protein “spilling” into the urine
  • Severe swelling in parts of the body, most noticeably around the eyes, hands, feet, and abdomen (called edema)
  • Weight gain due to a buildup of extra fluid
  • Fatigue
  • Loss of appetite
  • Low levels of protein in the blood (hypoalbuminemia)
  • Higher than normal fat and cholesterol levels in the blood (hyperlipidemia)

Nephrotic Syndrome can typically be diagnosed with a urine test.

Nephrotic Syndrome can be “primary” or “secondary” in nature.

Diseases that affect only the kidneys are called primary causes of Nephrotic Syndrome. Doctors often call these diseases “idiopathic,” which means that they arise from an unknown cause. Some of these diseases include:

  • Minimal Change Disease (MCD) – most common in children
  • Focal Segmental Glomerulosclerosis (FSGS)
  • Membranous Nephropathy (MN) – most common in adults
  • IgA Nephropathy (IgAN)

Secondary Nephrotic Syndrome is caused by an underlying, systemic condition like diabetes, lupus, HIV, and others.

The Kidney Health Gateway is a website owned and operated by NephCure Kidney International. The purpose of this website is to help patients with rare forms of primary Nephrotic Syndrome get connected to expert care and cutting-edge treatment options. By answering a few questions about you or your loved one’s condition, we can provide you with a list of clinical trials and/or expert doctors in your area.

If you have additional questions, please visit or email


Still have questions?
See other frequently asked questions