Observational Study
researchers track health outcomes over time in groups of participants to look for patterns that help us better understand a disease.
NEPTUNE
Nephrotic Syndrome Study Network (NEPTUNE)
The purpose of this study is to gather long-term observational data in order to help understand the biology behind nephrotic syndrome.
Observational Study
researchers track health outcomes over time in groups of participants to look for patterns that help us better understand a disease.
NEPTUNE
Nephrotic Syndrome Study Network (NEPTUNE)
The purpose of this study is to gather long-term observational data in order to help understand the biology behind nephrotic syndrome.
Eligibility Criteria
Patient Population
Primary focal segmental glomerulosclerosis (FSGS), membranous nephropathy (MN), or minimal change disease (MCD)
Age
0 — 26+
History of transplant allowed?
Yes, No
History of dialysis allowed?
Yes, No
eGFR
15 — > 60
UPCR
1.0 or Less — 3.0 or Above
Permitted medication history
Ace Inhibitors/ARB, Prednisone (Steroids), Abatacept, Acthar, Cellcept (AKA Mycophenolate), Cytoxan (Cyclophosphamide), Prograf (AKA Tacrolimus), Rituximab (AKA Rituxan), Other, None
Patient should be
Treatment Resistant, Steroid Dependent, Neither of These
About the Drug
What is involved for the patient
Patients will be asked to allow researchers to access medical history. The study team may also collect biosamples (blood, urine, biopsy tissue). Visits may be in conjunction with normally scheduled appointments, but additional study visits may be required.
Sponsor
The University of Michigan
Target Enrollment
1200
About the Trial
Study Goal
NEPTUNE seeks to increase the understanding and improve treatment of rare forms of Nephrotic Syndrome.